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Others lose less, especially if they were previously eating in a deficit and have less initial water weight to release
B12 is included for energy and because it is cheap, well tolerated and gives the injection a perceptible effect though only patients who are actually deficient should expect a real energy change from it
J Control Release 162:575581
Some people report not feeling as thirsty as before starting treatment, which may contribute to constipation
Severe new weakness, numbness, or paralysis in a leg, concern for vascular or neurologic emergency
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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