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No analysis was conducted in the subgroup of patients with HF at baseline (approximately 14%) to determine whether treatment with liraglutide was associated with any change of severity of HF and/or cardiovascular mortality

As for complications, women who'd discontinued a GLP-1 prior to pregnancy had a 30% higher risk of developing diabetes while pregnant, a 29% higher risk of blood pressure issues during pregnancy, and a 34% higher risk for preterm delivery, the study found

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IGF-1 elevation persists for 9-11 days following a single dose

doi: 10.1038/nm727 6 GasbjergLSChristensenMBHartmannBLanngARSparre-UlrichAHGabeMBNet al