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and broad transcriptional effects, with gene-expression analyses identifying modulation of expression patterns associated with antioxidant defense, DNA repair, and tissue remodeling

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PMID 20200426

The peptide inhibits nuclear factor-B (NF-B) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor- (PPAR-), which promotes inflammatory resolution

Some find that ongoing maintenance helps keep energy levels consistent and prevents the return of fatigue or sluggishness