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In microdosing, your healthcare provider may recommend administering the medication every 10 or 14 days

They are typically free and widely available from manufacturers, healthcare providers, or pharmacies

Dose reduction or discontinuation may be necessary if you develop: Persistent, intolerable gastrointestinal symptoms despite supportive measures Acute pancreatitis (discontinue permanently) Severe hypoglycemia, particularly if taking concurrent insulin or sulfonylureas Acute kidney injury or worsening renal function Gallbladder disease symptoms (abdominal pain, jaundice) Diabetic retinopathy complications (particularly with semaglutide) Severe hypersensitivity reactions including anaphylaxis or angioedema Pregnancy or plans for pregnancy (for semaglutide, discontinue at least two months before planned conception

The dose is increased by 0.6 milligrams each week until the maintenance dose of 3.0 milligrams is reached

Endocrinol.: The maintenance of long-term weight loss after semaglutide withdrawal in obese women with PCOS treated with metformin: a 2-year observational study Medscape: Help Patients Prevent Weight Gain After Stopping GLP-1s