A., Rmer, J., Ahnfelt-Rnne, I., Ohlsson, C., & Jansson, J
"Obesity is a chronic, relapsing disease, and clinical trials have shown that sudden discontinuation of semaglutide or tirzepatide results in weight regain - up to two-thirds of the lost weight within one year - along with reversal of cardiometabolic improvements," says Silvana Obici, MD, the chief of the division of endocrinology at Stony Brook Medicine and the medical director of the Stony Brook University Hospital Diabetes Center, in Stony Brook, New York
Most of the weight back tends to come on within the first year after stopping
maridebart and cafraglutide, a dual GIP receptor antagonist and GLP-1 receptor agonist
Reported Side Effects Reported side effects may include: Injection-site irritation when injectable products are used Headache Temporary fatigue Digestive discomfort in some users These effects are typically described as mild, but any unexpected reaction should be discussed with a healthcare professional