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The first stall window for tirzepatide users commonly occurs around months 2 to 4, often during the dose escalation phase
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Notably, only a slight impairment in glucose-induced Ca 2+ responses was observed in Trpm5 / mouse islets (ESM Fig
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[19] Eli Lilly and Company (2021) A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight (SURMOUNT-1)
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