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To increase the plasma half-life by avoiding renal elimination, GLP-1 analogs were modified by adding acyl groups (liraglutide and semaglutide) or large molecules such as albumin (albiglutide) and the Fc portion of IgG (dulaglutide)
Water plays a key role in transporting hormones, developing follicles, and thinning out biological fluids
The presence of chronic health conditions like heart disease, high blood pressure, and kidney disease also plays a significant role when deciding on an appropriate GLP-1 medication
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