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While supplements are usually given as tablets, your doctor may recommend B12 injections, depending on your situation

The classic symptoms of B12 deficiency are persistent fatigue, tingling or numbness in the hands and feet, problems with memory and concentration, mouth ulcers, a sore red tongue, and pale or yellow-tinged skin

Both methods can improve B12 levels, but professional injections may suit those with specific health concerns

According to the 2025 meta-analysis by Alfalasi and colleagues, sublingual B12 showed an approximate 199% mean increase in serum B12 compared to approximately 307% for intramuscular injections

Navigate the landscape of B12 Shots & B12 Injections: The Good, Bad, and Alternative