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In theory, the difference in the effects might be attributed to a limited set of upstream and downstream effector proteins in erythrocytes compared with nucleated cells [84]

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Studies conducted in mice and human foreskin fibroblasts have revealed that S-acetyl-glutathione molecules are taken up directly by cells with subsequent conversion to glutathione by cleavage of the acetyl bond within the cell

After the folate cycle, through the interconnection with the methionine cycle involving the entry of cobalamin (vitamin B12), folic acid is again synthesised