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Substantial weight loss may also affect DOAC dose criteria for some agents (e.g., apixaban and edoxaban in patients 60 kg) and warrants clinical review

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This inflammation interferes with the normal digestion and absorption of nutrients, which can lead to symptoms like vomiting, diarrhea, and weight loss

Effect of semaglutide on the Pharmacokinetics of Metformin, Warfarin, Atorvastatin and Digoxin in Healthy Subjects