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Isatuximab binds to the CD38 epitope via its gamma heavy chains, inducing cell death through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) and apoptosis 146,147

This includes the release of pro-inflammatory cytokines like IL-6 and TNF-alpha, which can cross the blood-brain barrier and cause severe neuroinflammation

Injection-site irritation is the most commonly reported side effect

After the patients peaceful passing, the daughter personally reached out to express her gratitude

While keeping the skin pinched, slowly push the plunger on the syringe to push the medication into your subcutaneous tissue