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Semaglutide doses are measured in milligrams at much lower absolute amounts (0.25mg to 2.4mg weekly) compared to tirzepatide (2.5mg to 15mg weekly)

The higher dose was developed because while the 2.4-milligram shot is effective, "some individuals do not reach their therapeutic goals" at that dose, according to results published last year in the medical journal Lancet Diabetes & Endocrinology

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