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Novo spent so much time and money on this trial just to prove that a competitor is better
D.ShanahanF.et al
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The associated shift in the cellular redox state may cause the activation of Nrf2, leading to this additional positive effect on metabolism of high doses of thiamine disulfides, compared to thiamine
This suggests that M pro might be particularly efficient at disrupting GSH synthesis, as compared to action at some of the other target sites predicted here, thereby contributing to the clinical findings in COVID-19 (7)
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