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They stimulate insulin production and block secretion of the hormone glucagon, which raises blood sugar levels (and also slows digestion and curbs appetite)

The tradeoff is that more receptors also means more side effects, especially nausea and (for retatrutide) unusual skin sensations

This is among the more speculative areas of research

Regular check-ups, maintaining good hydration, managing blood sugar levels, and practicing good hygiene are all important steps

Retatrutide, a GIP, GLP-1, and glucagon receptor agonist, for the treatment of type 2 diabetes: a randomised, double-blind, placebo-controlled, Phase 2 trial