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The maintenance frequency approach represents hybrid strategy where initial intensive treatment (daily application for 3-6 months) establishes improvements, then reduces to maintenance schedule (2-3 times weekly or every other day) rather than complete discontinuation

GHK-Cu is also shown to stimulate collagen and elastin, smoothing and firming the skin over time without the potential skin irritation of prescription tretinoin or over-the-counter retinol

Characterization of disease burden, comorbidities, and treatment use in a large, US-based cohort: results from the Corrona Psoriasis Registry

Yuksel, C., et al

Products are shipped in plain packaging and accompanied by COA documentation