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doi: 10.1016/j.scitotenv.2023.167043 182 HuCLiuMTangLLiuHSunBChenL
387 2 2.5mg1INJE800021,10011 3 3mg6RYBE350028,02755011 GLP-1 GLP-1 1 1 1 GLP-1 SU GLP-1 GLP-1 GLP-1 SNS SNS SNS vs 12kg 301 vs 138kg 1 : : : GLP-1 GLP-1 GLP-11 : 1 10,000 30,000 : 1 25,000 50,000 : 1 30,000 60,000 SNS2,980 GLP-1 GLP-1 LINE GLP-1 GLP-1 GLP-1FAQ GLP-1 GLP-1 GLP-1 2 GLP-1 GLP-1 HbA1c GLP-1 GLP-1 GLP-1 [ ] [ ] [ ] [ ] [ ] [ ] [ ] 3
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In laboratory and pre-clinical research settings, FOXO4-DRI is used as the primary peptide tool for selective senescent cell elimination a strategy known as senolysis
34, 35, 36, 37, 38, 39 However, it is unknown if GLP-1R occurs on PSCs in normal pancreas, on activated PSCs in AP or CP or if this does occur, whether the GLP-1R agonists affect the PSC signaling cascade, PSC growth or ability to release inflammatory mediators
