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Of note, KD of ALOX15 and inhibition of 15LO1 decreased GPX4 protein expression, consistent with less need for peroxidase activity

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Toxicity of Biologically Active Peptides and Future Safety Aspects: An Update

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Thus, the leading causes of death in patients with thyroid dysfunctions are the consequences of atherosclerosis acceleration and the worsening of pre-existing cardiovascular and central nervous system diseases (77, 78)

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