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New research from 23and ME sheds a light on why GLP-1 weight-loss drugs work differently across patients, with two studies suggesting that genetic variation and cardiovascular mechanisms independent of weight loss may both play significant roles in determining individual outcomes

And it's a series of studies with different designs and populations to look, in randomized controlled trials that's the highest level evidence at what this drug would do for individuals with obesity, individuals with obesity who also had diabetes, what about if we add intensive lifestyle therapy to it, what would happen if we stopped the medication, what about individuals living with arthritis or with heart failure or heart disease

It seems to decrease the total number of fat cells and reduce the amount of fat they hold

They put my husband on [a] standard dose for diabetes and he was just so sick, reads a Reddit post by MenloShark25, who says theyre receiving their prescription through telehealth provider Midi

Serotonin also affects pancreatic enzyme release