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FDA-approved medications undergo a regulatory review process to ensure safety, dosing, manufacturing, labeling, and effectiveness
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It is sold in weekly subcutaneous injections at five doses from 2.5 mg through 15 mg, and the Phase 3 SURMOUNT trials showed average weight loss of roughly 20 to 22 percent at the highest dose over 72 weeks
However, lactate accumulated during the ischemic phase itself, when oxygen tension is absent, cannot fuel oxidative metabolism
Typically, application of one 1mg dose once weekly constitutes the intermediate therapeutic dose for the restoration of physiological equilibrium during the escalation phase
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