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Perils of biotin supplementation
Brands like Ozempic, Mounjaro and Wegovy do this by mimicking the body's natural hormones, sending a signal to the brain that the person is full, and as such, cutting down how much food they're consuming
Specifically, SIRT3 deacetylates and inhibits aldehyde dehydrogenase 2, which prevents the conversion of acetaldehyde to acetate, potentially leading to acetaldehyde toxicity 183
Arthritis Care Res (Hoboken) 64(4):465474
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