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This efficiency is especially valuable in laboratories managing high research volumes or long-term studies , where budget allocation and material conservation are ongoing considerations

Notably, non-internalized NPs like pristine SiO 2 NPs [452] and LaVO 4 :Eu 3+ NPs [459] can still trigger eryptosis, relying on Ca 2+ signaling, which can be mediated by their direct influence on Piezo1 channels

However, ongoing research continues to explore its various potential uses

It is sometimes used to improve muscle performance in animals like racing horses, and it is also used to increase milk production in dairy cows