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People with the following conditions should avoid it: A personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2)
The global SUSTAIN and PIONEER phase III clinical trial programs have studied the effectiveness and safety of once-weekly subcutaneous semaglutide and once-daily oral semaglutide
The total weekly amount stays the same, but dividing it into two smaller injections reduces the spike in side effects that a single weekly dose can cause
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