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Uninsured costs range from the mid-hundreds to low thousands per month Tirzepatide GLP-1 & GIP dual receptor agonist : (as semaglutide, plus fat metabolism, insulin sensitivity, and enhanced satiety) SURMOUNT 1 20.9% (72 weeks) SURMOUNT 5 (40 weeks, BMI 40): -20.2% ~2021% average loss 20% loss in ~36% of users 25% in ~25% (up to 40% in SURMOUNT-3) 15mg weekly Nausea (52%) Diarrhea (33%) Vomiting (25%) Constipation (25%) Higher rate of initial GI symptoms vs

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Prophylactic supplementation is generally rarely required after cholecystectomy