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GLP-1 RAs were identified in the DRUG files using generic or brand names, including exenatide (BYETTA, BYDUREON BCISE), liraglutide (VICTOZA, SAXENDA, XULTOPHY), lixisenatide (LYXUMIA, ADLYXIN, SOLIQUA), dulaglutide (TRULICITY), semaglutide (OZEMPIC, RYBELSUS, WEGOVY), and tirzepatide (MOUNJARO, ZEPBOUND)

This sustained elevation in metabolic rate helps prevent the adaptive thermogenesis (metabolic slowdown) that typically accompanies significant weight loss and contributes to weight regain

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For general context only, the broader pharmacological literature on structurally analogous GLP-1-class peptides suggests that reconstituted peptide preparations are typically less stable than their lyophilised counterparts and that refrigerated storage is essential

Recent clinical studies such as PIONEER and SUSTAIN analysis have shown extremely high rates of blood clots in patients with diabetes, says Raj Singh, MD, a primary care provider at HEALOR and medical director at RAREV Medical Spa in Las Vegas, Nevada