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Hyperhomocysteinemia, a risk factor for atherosclerosis in chronic uremic patients

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CJC-1295 (with DAC) is a modified GHRH analogue with an extended half-life achieved via Drug Affinity Complex (DAC) technology that covalently binds to serum albumin

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Rule of 5 Limits to a series of molecular properties of drugs (logP, molecular weight, hydrogen bond donors and acceptors), suggested by Lipinski to increase the likelihood of good oral absorption

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Nature 409:307312

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