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Subjective improvements in sleep onset time, sleep duration, and sleep quality commonly appear within the first week of administration
Hydroquinone produces faster visible results (48 weeks) because it acts at the melanocyte surface, but glutathione offers systemic antioxidant benefits and lower risk of rebound hyperpigmentation after discontinuation
doi: 10.1016/j.jconrel.2022.08.048 61 CharalambousAMpekrisFPanagiMVoutouriCMichaelCGabizonA
No saturation behavior for GSSG was previously detected for the fusion construct between rxYFP and ScGrx1 31 , which makes sense considering that PfGrx and many other glutaredoxins are at least two orders of magnitude more active than ScGrx1 (Table 1) 14,56