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Como explica Andreea Ciudin Mihai , coordinadora de la Unidad de Tratamiento de la Obesidad del Servicio de Endocrinologa y Nutricin del Hospital Universitario Vall d' Hebron, e l GLP-1 endgeno se sintetiza en las clulas L del intestino terminal, tras una ingesta , y su vida media es de unos minutos, suficiente para estimular la liberacin de insulina dependiente de glucosa, y activar sus receptores en el resto de rganos para los efectos postprandiales