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A 2017 analysis in the Journal of Medicinal Chemistry described curcumin as a "pan-assay interference compound" (PAINS) that produces false positives in many in-vitro screening assays [15]

Wilson L, Stewart W, Dams-OConnor K, Diaz-Arrastia R, Horton L, Menon DK, et al

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Rinse thoroughly and pat dry

The concurrent use of berberine and phentermine has not been extensively studied in formal clinical trials, and there is no official guidance from UK regulatory bodies such as the MHRA or NICE regarding this specific combination