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Reducing oxidative stress is crucial because it influences the activity of tyrosinase

It shields the cells against oxidative stress and promotes the clearance of pathways in the liver

Its role in cellular protection makes it a vital molecule in understanding and preventing chronic diseases such as cancer, cardiovascular disorders, and neurodegenerative diseases like Alzheimers

Function, Oxidative, and Inflammatory Stress Parameters in Immune Cells as Predictive Markers of Lifespan throughout Aging

Also, genetic modifiers of poly GR toxicity in Drosophila identified APE1 and other DNA repair proteins (Ku80 and ERCC1) as suppressors of GR toxicity (Lopez-Gonzalez et al., 2019)