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By altering the brains hunger signals, topiramate helps reduce how much food a person wants to eat, leading to a lower calorie intake over time

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Semaglutide was also associated with reduced craving and drinks per day Data from participants daily logs indicated that those receiving semaglutide had less average alcohol craving each week (small effect size), and on average drank less drinks per drinking day while also having greater reductions in heavy drinking days over time (large effect sizes

GLP-1 receptor agonists bind to GLP-1 receptors in the pancreas, stimulating insulin secretion when blood glucose levels are elevated whilst simultaneously suppressing glucagon release