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Within healthcare, landmark trials like SELECT have demonstrated that GLP-1 drugs can reduce the risk of diabetes by 73% and cardiovascular events by 20%
Treatments that don't produce the measurable lymphatic clearing and circumference reduction that indicate effective fat elimination leaving metabolic byproducts in the tissue
In particular, LEAP2 (liver-expressed antimicrobial peptide 2), an endogenous antagonist of the ghrelin receptor GHSR, has emerged as a potential target for mitigating the weight regain often observed after discontinuation of GLP-1-based therapies [22,23]
& Saykin, A
This predominantly manifests as gastrointestinal symptoms such as nausea, vomiting, and constipation, which can be severe for some people
