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This reflects the fact that GLP-1 agonists correct a physiological state (impaired satiety signaling and elevated ghrelin) that returns when the medication is removed
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It seems to be important for controlling hunger and telling the brain when the stomach is full
& Gores, G
They compared patients starting on GLP-1 RAs with those starting on SGLT-2 inhibitors, DPP-4 inhibitors, sulfonylurea, and basal insulin
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