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1 Table 1 Comparison of Peptide and Small Molecule GLP-1 Receptor Agonists GLP-1, glucagon-like peptide-1

A peptide can quiet the symptoms for a while, but finding the root cause is what makes results last

At present, it remains unclear whether these changes in PSCs contribute to the development of pancreatitis seen in patients with chronic use of GLP-1R agonists, or whether they could lead to complications of the increased PSCs proliferation due to long-term use of GLP-1 agonists

Price : Without insurance, both drugs are expensive, typically costing nearly $1,000 per month out-of-pocket, though manufacturer savings cards are sometimes available for eligible patients with commercial insurance

Dziennis and Alkayed, 2008)