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The most frequent genetic causes of SLOCA are heterozygous GAA expansions in FGF14 (spinocerebellar atrophy type 27B) and biallelic expansions in RFC1 (cerebellar ataxia with neuropathy and vestibular areflexia (CANVAS))

This localized depletion is strongly correlated with increased ventricular lactate, pointing to severe neuroinflammation, an overwhelmed central nervous system antioxidant network, and a direct physiological explanation for the profound cognitive dysfunction and "brain fog" experienced by patients

Glutathione is a master antioxidant

Microdosing The microdosing approach uses much lower amounts, often 0.5 to 1.5 mg per dose, for specific applications like inflammation management

Symptoms of a Sluggish Metabolism: Easy weight gain, difficulty losing weight, low energy, and feeling cold