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Preclinical data from the CagriSema program demonstrate pronounced additive metabolic endpoint changes when both pathways are activated simultaneously, exceeding either agent alone in study models
These findings support morin hydrates potential as an adjuvant therapy to mitigate cisplatin-induced toxicity (170)
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& Young, T
As noted, the Wnt/-catenin pathway is a genuine master switch for anagen: stabilizing -catenin in dermal papilla cells accelerates hair growth in experimental models, and the pathways activity distinguishes hair-inducing from non-inducing papilla cells
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