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Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration
Ferroptosis suppressor protein 1 (FSP1) previously called apoptosis-inducing factor mitochondria-associated 2 (AIFM2) confers protection against ferroptosis by complement the loss of GPX4
N., Song, Y., Chen, W., Wang, G., Edden, R
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