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HARMONY 3: 104-week randomized, double-blind, placebo- and active-controlled trial assessing the efficacy and safety of albiglutide compared with placebo, sitagliptin, and glimepiride in patients with type 2 diabetes taking metformin
It is also cost savings (you use less medication over time) and more data per dose level (you get 6 to 8 weeks of weight loss data instead of 4, making it easier to determine whether a dose is truly working or has plateaued)
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Porter et al., 2013)
Arousal begins in the brain, and for many patients the limiting factor is not blood flow at all
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