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In vivo, intravenous administration of Leg@J-DBCO (10 mg/kg) and CTB@P-N (10 mg/kg) every 2 days for 8 days achieved 78.7% tumor inhibition in HeLa models, accompanied by selective BRD4 degradation and favorable biosafety profiles [87]
382,383 An in-depth understanding of the underlying mechanisms of cellular pyroptosis is essential to determine its role in the pathogenesis of DPN and develop effective therapeutic agents targeting the pyroptosis signaling pathway to alleviate neuropathic symptoms
doi:10.1177/11786388251345518
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