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As of early 2025, a systematic review of the musculoskeletal literature identified 544 published BPC-157 articles from 1993 to 2024, of which 36 focused on orthopaedic outcomes and only one was a human clinical study [16]
doi: 10.1016/j.phrs.2022.106135 174 MoisseievEAndersonJDOltjenSGoswamiMZawadzkiRJNoltaJAet al
This paradox suggests that oral collagen may stimulate broader systemic collagen synthesis pathways beyond direct peptide delivery
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