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A tissue distribution study revealed no statistically significant difference in DiR distribution between the control liposomes and COXP liposomes in heart, liver, and spleen while significantly higher distribution was observed in the brain (~9 fold) and kidneys (~9 fold) for DiR delivered by COXP liposomes when compared with that from the control liposomes

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As purine/pyrimidine metabolites are required for transcriptional reprogramming 36 , some anabolic metabolisms for RNA and protein synthesis would also be supported by increases of purines and pyrimidines

Nationwide, there are differences in laws and their interpretation