Three medications represent this progression: Semaglutide (single agonist, 15% average weight loss), Tirzepatide (dual agonist, 22.5% weight loss), and Retatrutide (triple agonist, 28.7% weight loss)
Are You a Candidate for Semaglutide Treatment
What is a reasonable daily target
Importantly, older adults adhere better to, and maintain greater weight loss from, lifestyle interventions [70,71,72], and in the real-world setting, the National Institute for Health and Care Excellence (NICE) report that older participants lose more weight than younger adults during BWMPs [73]
If side effects resolve but you notice no benefits by month three, the product may not be right for your biology