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The peptide primarily activates melanocortin receptor subtypes MC1R, MC3R, MC4R, and MC5R, with particular affinity for MC3R and MC4R at therapeutic doses
What sets this review apart is its focus on the translational dimension: highlighting recent advances in delivery systems to overcome bioavailability challenges and identifying gaps that must be addressed through clinical research
doi: 10.2337/diabetes.52.1.102 125 FarillaLHuiHBertolottoCKangEBulottaADi MarioUet al
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