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In aged human pinealocytes, Epitalon selectively safeguarded cells from degenerative changes, suggesting a tissue-specific rejuvenating effect on the very gland responsible for circadian control

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kawamurai occurs in exons 1 and 3

Necrosis, typically resulting from severe injury, manifests as uncontrolled cell death with cellular content leakage, whereas ferroptosis proceeds as a regulated process driven by oxidative stress and iron overload, primarily through ROS-induced lipid damage (14)

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