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Yes semaglutide (Wegovy) and liraglutide (Saxenda) are licensed GLP-1 receptor agonist medicines available through NHS specialist weight management services for eligible patients, in line with NICE TA875 and NICE TA664 respectively
They: Increase insulin secretion in response to meals Suppress glucagon, a hormone that raises blood sugar Slow gastric emptying, which helps you feel full longer Reduce appetite, often leading to weight loss This combination makes them effective for both diabetes management and weight reduction Nausea is a common side effect when starting GLP-1 medications because they slow digestion and affect appetite signals in the brain
Nitric Oxide 32 , 3642 (2013)
Some studies indicate that approximately 20-30% of weight loss from GLP-1 therapy may come from lean masssimilar to dietary interventions
Vitamin B deficiencies B12 deficiency Pernicious anemia (supportive) Malabsorption disorders 3
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