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Semaglutide 2.4 mg (Wegovy) is approved under NICE technology appraisal TA875, and tirzepatide (Mounjaro) has also received a NICE technology appraisal for weight management
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The authors inferred that the increased plasma Met concentration in the RPM group, likely supplied the elevated demand in the mammary tissue required to synthesize cytoprotective proteins, such as heat-shock proteins, which are necessary for cellular defense against thermal stress (Pate et al., 2021)
If youre ever concerned about your weight we recommend speaking to your healthcare team, they will be able to assess your condition and make changes to your treatment plan, if necessary
The second submission was in response to a Complete Response Letter issued by the FDA in December 2019
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