Ajoene is also an antifungal medication that is safe and successful in treating chromoblastomycosis and dermatophytosis (53)
Sequencing was performed using a HiSeq 2500 (Illumina), with a read length of 300 bp paired-end reads and at least 25,000 tags per sample
Zilka O, Shah R, Li B, Friedmann Angeli JP, Griesser M, Conrad M et al (2017) On the mechanism of cytoprotection by ferrostatin-1 and liproxstatin-1 and the role of lipid peroxidation in ferroptotic cell death
Therefore, this suggests that the metabolic stress induced by GLS1 knockdown can trigger autophagy as a survival mechanism
It also shows potential for promoting tissue repair, reducing the impact of aging, and may have applications in supporting cognitive and metabolic health