The pathway analysis by KEGG on differentially expressed proteins suggested that the significantly affected pathways were steroid hormone biosynthesis, propanoate metabolism, systemic lupus erythematosus, non-alcoholic fatty liver disease (NAFLD), fatty acid degradation, fatty acid metabolism, citrate cycle (TCA cycle), carbon metabolism, fat digestion and absorption, Parkinsons disease (PD), oxidative phosphorylation, ubiquinone and other terpenoid-quinone biosynthesis, alcoholism (Fig
Mller TD, Finan B, Bloom SR, DAlessio D, Drucker DJ, Flatt PR, et al
Behavior Mice were initially trained in the wheel cages for two weeks to allow them to establish familiarity with the wheel and a baseline level of running
The scale of the transformation is striking
It does not cite sources for the specific percentage losses it quotes, so those figures should be treated as unverified