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Moreover, to achieve temperature-responsive transcriptional regulation of heterologous expression, two thermoregulated systems were engineered: (1) the phage-derived cI857/PL system employing a thermosensitive repressor, and (2) a synthetic P IbpA variant incorporating Pseudomonas aeruginosa IbpA-5UTR modifications
R., Fadel, P
The varying expression levels of these genes could potentially serve as indicators of tumor progression and severity [136]
Factors That Deplete Glutathione Levels Glutathione reserves can decline due to multiple factors
Low GSH, neutrophil infiltration, myeloperoxidase activity and inflammation increase oxidative stress overwhelming the antioxidant defense, and hypochlorous acid mediated GSH oxidation and its attachment to proteins contribute to further GSH deficiency (114)
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