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GLP-1 receptors are widely distributed in other areas of the body, including the brain, gut, and kidneys, as well as the cardiovascular and immune systems, says Diana Isaacs, PharmD, an endocrine clinical pharmacy specialist at the Endocrine and Metabolism Institute at Cleveland Clinic in Ohio

148 Based on intention to treat analysis at 3 months, 31% of the patients reported improvement in the GRA scale, 15% in the ICSI, and 19% in the ICPI scores

This need is potentially more acute in early pregnancy as well

The side effect profile matters