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Through its metabolites, such as AFMK and 6-OHM, melatonin enhances GSH levels, a key antioxidant, and mitigates UVB-induced GSH depletion 198
4a) G6PD is commonly overexpressed in many myeloid and lymphoid malignancies leading to improved proliferation, but this effect can be abrogated by pharmacologic inhibition of G6PD 87
(PubMed) Smith AD, Smith SM, de Jager CA, et al
Furthermore, the results suggest that the homocysteinylation might be regulated by the thiol redox status
Hypoxia inhibits ferritinophagy, increases mitochondrial ferritin, and protects from ferroptosis
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